Further Information
Potassium voltage-gated channel subfamily A member 2, NGK1, Voltage-gated K(+) channel HuKIV, Voltage-gated potassium channel HBK5, Voltage-gated potassium channel subunit Kv12, KCNA2
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Potassium channels represent the most complex class of
voltage-gated ion channels from both functional and structural
standpoints. Their diverse functions include regulating
neurotransmitter release, heart rate, insulin secretion, neuronal
excitability, epithelial electrolyte transport, smooth muscle
contraction, and cell volume. Four sequence-related potassium
channel genes - shaker, shaw, shab, and shal - have been identified
in Drosophila, and each has been shown to have human homolog(s).
This gene encodes a member of the potassium channel, voltage-gated,
shaker-related subfamily. This member contains six
membrane-spanning domains with a shaker-type repeat in the fourth
segment. It belongs to the delayed rectifier class, members of
which allow nerve cells to efficiently repolarize following an
action potential. The coding region of this gene is intronless, and
the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
- Denning, E.J., et al. Mol. Membr. Biol. 26(8):397-421(2009)
- Peters, C.J., et al. Channels (Austin) 3(5):314-322(2009)
- Martos, V., et al. Proc. Natl. Acad. Sci. U.S.A. 106(26):10482-10486(2009)
- Stirling, L., et al. Mol. Biol. Cell 20(12):2991-3002(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat
This KCNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-479 amino acids from the C-terminal region of human KCNA2.
3737
Potassium voltage-gated channel subfamily A member 2
KCNA2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
P16389
1345813
This antibody is purified through a protein A column, followed by peptide affinity purification.
Neuroscience
P16389
Optimal dilutions for each application to be determined by the researcher.