Further Information
Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, bHLHa26, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2, dHAND, HAND2, BHLHA26, DHAND
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
HAND2 belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.
- McFadden, D.G., et al., Development 127(24):5331-5341 (2000). Firulli, A.B., et al., Nat. Genet. 18(3):266-270 (1998). Russell, M.W., et al., Biochim. Biophys. Acta 1443(3):393-399 (1998). Srivastava, D., Trends Cardiovasc Med(1-2), 11-18 (1999). Srivastava, D., et al., Cold Spring Harb. Symp. Quant. Biol. 67, 121-125 (2002).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Zebrafish
This HAND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the C-terminal region of human HAND2.
9464
Heart- and neural crest derivatives-expressed protein 2
HAND2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
P61296
47117699
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Neuroscience
P61296
Optimal dilutions for each application to be determined by the researcher.