ProSci

HRH4 Antibody

Product Code:
 
PSI-58-895
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

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PSI-58-895-400ul400ul£626.00
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Further Information

Additional Names:
Histamine H4 receptor, H4R, HH4R, AXOR35, G-protein coupled receptor 105, GPRv53, Pfi-013, SP9144, HRH4, GPCR105
Application Note:
For WB starting dilution is: 1:1000
Background:
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Yu, B., et al. Br. J. Dermatol. 163(5):935-940(2010)
  • Gschwandtner, M., et al. Allergy 65(7):840-849(2010)
  • Yu, B., et al. Br. J. Dermatol. 162(5):1038-1043(2010)
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HRH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-256 amino acids from the Central region of human HRH4.
NCBI Gene ID #:
59340
NCBI Official Name:
Histamine H4 receptor
NCBI Official Symbol:
HRH4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q9H3N8
Protein GI Number:
14194819
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Growth Factor
Swissprot #:
Q9H3N8
User NOte:
Optimal dilutions for each application to be determined by the researcher.