Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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![Western blot analysis in ZR-75-1 cell line lysates (35ug/lane). Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).](https://www.prosci-inc.com/static-images/58-011_1.jpg)
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![CYSLTR1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. CYSLTR1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.](https://www.prosci-inc.com/static-images/58-011_2.jpg)
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
Cysteinyl leukotriene receptor 1, CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, G-protein coupled receptor HG55, HMTMF81, CYSLTR1, CYSLT1
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are
important mediators of human bronchial asthma. Pharmacologic
studies have determined that cysteinyl leukotrienes activate at
least 2 receptors, the protein encoded by this gene and CYSLTR2.
This encoded receptor is a member of the superfamily of G
protein-coupled receptors. Activation of this receptor by LTD4
results in contraction and proliferation of smooth muscle, oedema,
eosinophil migration and damage to the mucus layer in the lung.
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Boulay, M.E., et al. Prostaglandins Leukot. Essent. Fatty Acids 83(1):15-22(2010)
- Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
- Hasegawa, S., et al. Platelets 21(4):253-259(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This CYSLTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-172 amino acids from the Central region of human CYSLTR1.
10800
Cysteinyl leukotriene receptor 1
CYSLTR1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Q9Y271
20138087
This antibody is purified through a protein A column, followed by peptide affinity purification.
Neuroscience,Growth Factor
Q9Y271
Optimal dilutions for each application to be determined by the researcher.