ProSci

YY1 Antibody

Product Code:
 
PSI-60-466
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: Daudi whole cell lysate Lane 3: HuT78 whole cell lysate Lane 4: Y79 whole cell lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: Daudi whole cell lysate Lane 3: HuT78 whole cell lysate Lane 4: Y79 whole cell lysate Lysates/proteins at 20 ug per lane.

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PSI-60-466-400ul400ul£626.00
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Further Information

Additional Names:
Transcriptional repressor protein YY1, Delta transcription factor, INO80 complex subunit S, NF-E1, Yin and yang 1, YY-1, YY1, INO80S
Application Note:
For WB starting dilution is: 1:2000
Background:
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
Background References:
  • Yu, H., et al. Mol. Cell. Biol. 30(21):5071-5085(2010)
  • Buira, S.P., et al. J. Neurochem. 115(1):283-295(2010)
  • Aoyama, T., et al. J. Biol. Chem. 285(39):29842-29850(2010)
  • de Nigris, F., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14484-14489(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This YY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of human YY1.
NCBI Gene ID #:
7528
NCBI Official Name:
Transcriptional repressor protein YY1
NCBI Official Symbol:
YY1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
P25490
Protein GI Number:
3915889
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Load Control Antibodies
Swissprot #:
P25490
User NOte:
Optimal dilutions for each application to be determined by the researcher.