Further Information
Receptor-type tyrosine-protein phosphatase R, R-PTP-R, Ch-1PTPase, NC-PTPCOM1, Protein-tyrosine phosphatase PCPTP1, PTPRR, ECPTP, PTPRQ
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
PCPTP1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene for this protein predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of the gene for this protein was reported to be regulated by the nerve growth factor, which suggested a function in neuronal growth and differentiation.
- Blanco-Aparicio, C., et al., J. Cell Biol. 147(6):1129-1136 (1999).
- Ogata, M., et al., J. Biol. Chem. 270(5):2337-2343 (1995).
- Shiozuka, K., et al., Gene 162(2):279-284 (1995).
- Sharma, E., et al., J. Biol. Chem. 270(1):49-53 (1995).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This PCPTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-265 amino acids from the N-terminal region of human PCPTP1.
5801
Receptor-type tyrosine-protein phosphatase R
PTPRR
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Q15256
134039192
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Neuroscience,Signal Transduction
Q15256
Optimal dilutions for each application to be determined by the researcher.