Further Information
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha, Diphosphoinositide kinase 2-alpha, PIP5KIII, Phosphatidylinositol 5-phosphate 4-kinase type II alpha, PI(5)P 4-kinase type II alpha, PIP4KII-alpha, PtdIns(4)P-5-kinase B isoform, PtdIns(4)P-5-kinase C isoform, PtdIns(5)P-4-kinase isoform 2-alpha, PIP4K2A, PIP5K2, PIP5K2A
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Phosphatidylinositol-4,5-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. TPIP5K2A is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. The protein is a member of the phosphatidylinositol-4-phosphate 5-kinase family.
- Rozenvayn, N., et al., J. Biol. Chem. 278(10):8126-8134 (2003).
- Boronenkov, I.V., et al., J. Biol. Chem. 270(7):2881-2884 (1995).
- Loijens, J.C., et al., Adv. Enzyme Regul. 36, 115-140 (1996).
- Divecha, N., et al., Biochem. J. 309 (Pt 3), 715-719 (1995).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Pig
This PIP5K2 Alpha (PIP5K2A) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-335 amino acids from the C-terminal region of human PIP5K2 Alpha (PIP5K2A).
5305
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
PIP4K2A
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
P48426
18266879
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Obesity,Signal Transduction
P48426
Optimal dilutions for each application to be determined by the researcher.