Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
No additional charges, what you see is what you pay! *
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available!
Contact us to find what you can save.
This product comes from:
United States.
Typical lead time:
14-21 working days.
Contact us for more accurate information.
- Further Information
- Documents
- Show All
Further Information
H(+)/Cl(-) exchange transporter 7, Chloride channel 7 alpha subunit, Chloride channel protein 7, ClC-7, CLCN7
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
The product of this gene belongs to the CLC chloride
channel family of proteins. Chloride channels play important roles
in the plasma membrane and in intracellular organelles. This gene
encodes chloride channel 7. Defects in this gene are the cause of
osteopetrosis autosomal recessive type 4 (OPTB4), also called
infantile malignant osteopetrosis type 2 as well as the cause of
autosomal dominant osteopetrosis type 2 (OPTA2), also called
autosomal dominant Albers-Schonberg disease or marble disease
autosoml dominant. Osteopetrosis is a rare genetic disease
characterized by abnormally dense bone, due to defective resorption
of immature bone. OPTA2 is the most common form of osteopetrosis,
occurring in adolescence or adulthood.
- Furthner, D., et al. Klin Padiatr 222(3):180-183(2010)
- Phadke, S.R., et al. Indian J. Med. Res. 131, 508-514 (2010) :
- Pangrazio, A., et al. Hum. Mutat. 31 (1), E1071-E1080 (2010) :
- Kajiya, H., et al. Pflugers Arch. 458(6):1049-1059(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
This CLCN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-720 amino acids from the C-terminal region of human CLCN7.
1186
H(+)/Cl(-) exchange transporter 7
CLCN7
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
89 kDa
P51798
12644301
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Signal Transduction
P51798
Optimal dilutions for each application to be determined by the researcher.