ProSci

GNAI2 Antibody

Product Code:
 
PSI-57-720
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
2 / 2
Western blot analysis of GNAI2 using rabbit polyclonal GNAI2 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GNAI2 gene.
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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
Western blot analysis of GNAI2 using rabbit polyclonal GNAI2 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GNAI2 gene.

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PSI-57-720-400ul400ul£626.00
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Further Information

Additional Names:
Guanine nucleotide-binding protein G(i) subunit alpha-2, Adenylate cyclase-inhibiting G alpha protein, GNAI2, GNAI2B
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only two are known so far.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • So, H.C., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (1), 103-113 (2010) :
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Kuszak, A.J., et al. J. Biol. Chem. 284(39):26732-26741(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This GNAI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-107 amino acids from the N-terminal region of human GNAI2.
NCBI Gene ID #:
2771
NCBI Official Name:
Guanine nucleotide-binding protein G(i) subunit alpha-2
NCBI Official Symbol:
GNAI2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
P04899
Protein GI Number:
121023
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P04899
User NOte:
Optimal dilutions for each application to be determined by the researcher.