ProSci

ITK Antibody

Product Code:
 
PSI-63-163
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Antibody is used in Western blot to detect ITK in CEM cell lysate.
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Antibody is used in Western blot to detect ITK in CEM cell lysate.

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PSI-63-163-400ul400ul£626.00
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This product comes from: United States.
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Further Information

Additional Names:
Tyrosine-protein kinase ITK/TSK, Interleukin-2-inducible T-cell kinase, IL-2-inducible T-cell kinase, Kinase EMT, T-cell-specific kinase, Tyrosine-protein kinase Lyk, ITK, EMT, LYK
Application Note:
For WB starting dilution is: 1:1000
Background:
ITK is an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.
Background References:
  • Brazin, K.N., et al., Proc. Natl. Acad. Sci. U.S.A. 99(4):1899-1904 (2002).
  • Hawkins, J., et al., Protein Expr. Purif. 22(2):211-219 (2001).
  • Janis, E.M., et al., Genomics 23(1):269-271 (1994).
  • Gibson, S., et al., Blood 82(5):1561-1572 (1993).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ITK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human ITK.
NCBI Gene ID #:
3702
NCBI Official Name:
Tyrosine-protein kinase ITK/TSK
NCBI Official Symbol:
ITK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
Q08881
Protein GI Number:
585361
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q08881
User NOte:
Optimal dilutions for each application to be determined by the researcher.