ProSci

SIT1 Antibody

Product Code:
 
PSI-58-721
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

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PSI-58-721-400ul400ul£626.00
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Further Information

Additional Names:
Signaling threshold-regulating transmembrane adapter 1, SHP2-interacting transmembrane adapter protein, Suppression-inducing transmembrane adapter 1, gp30/40, SIT1, SIT
Application Note:
For WB starting dilution is: 1:1000
Background:
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.
Background References:
  • Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)
  • Tedoldi, S., et al. Blood 107(1):213-221(2006)
  • Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
  • Tao, W.A., et al. Nat. Methods 2(8):591-598(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This SIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the C-terminal region of human SIT1.
NCBI Gene ID #:
27240
NCBI Official Name:
Signaling threshold-regulating transmembrane adapter 1
NCBI Official Symbol:
SIT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
Q9Y3P8
Protein GI Number:
74753488
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y3P8
User NOte:
Optimal dilutions for each application to be determined by the researcher.