ProSci

Mouse Bmpr1b Antibody

Product Code:
 
PSI-58-363
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Hela cell line lysates (35ug/lane).
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Western blot analysis in Hela cell line lysates (35ug/lane).

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PSI-58-363-400ul400ul£626.00
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Further Information

Additional Names:
Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, Activin receptor-like kinase 6, ALK-6, Serine/threonine-protein kinase receptor R6, SKR6, CDw293, Bmpr1b, Acvrlk6
Application Note:
For WB starting dilution is: 1:1000
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMPS/OP-1.
Background References:
  • Chiang, P.M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(37):16320-16324(2010)
  • Witte, F., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14211-14216(2010)
  • Libusova, L., et al. Development 137(14):2297-2305(2010)
  • Suzuki, Y., et al. J. Cell. Sci. 123 (PT 10), 1684-1692 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken
Immunogen:
This Mouse Bmpr1b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from the Central region of mouse Bmpr1b.
NCBI Gene ID #:
12167
NCBI Official Name:
Bone morphogenetic protein receptor type-1B
NCBI Official Symbol:
Bmpr1b
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
P36898
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P36898
User NOte:
Optimal dilutions for each application to be determined by the researcher.