ProSci

HEMGN Antibody

Product Code:
 
PSI-56-873
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in A549 cell line lysates (35ug/lane).
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Western blot analysis in A549 cell line lysates (35ug/lane).

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PSI-56-873-400ul400ul£626.00
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Further Information

Additional Names:
Hemogen, Erythroid differentiation-associated gene protein, EDAG-1, Hemopoietic gene protein, Negative differentiation regulator protein, HEMGN, EDAG, NDR
Application Note:
For WB starting dilution is: 1:1000
Background:
HEMGN regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
Background References:
  • Ding, Y.L., et al. J. Cell. Biochem. 110(4):866-874(2010)
  • Moreno, L.M., et al. Hum. Mol. Genet. 18(24):4879-4896(2009)
  • Lowe, J.K., et al. PLoS Genet.(2), E1000365 (2009) :
  • Li, C.Y., et al. Biochim. Biophys. Acta 1779(10):606-615(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HEMGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 420-449 amino acids from the C-terminal region of human HEMGN.
NCBI Gene ID #:
55363
NCBI Official Name:
Hemogen
NCBI Official Symbol:
HEMGN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
Q9BXL5
Protein GI Number:
74752432
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9BXL5
User NOte:
Optimal dilutions for each application to be determined by the researcher.