ProSci

CORO2A Antibody

Product Code:
 
PSI-57-143
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in CEM cell line lysates (35ug/lane).
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Western blot analysis in CEM cell line lysates (35ug/lane).

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PSI-57-143-400ul400ul£626.00
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Further Information

Additional Names:
Coronin-2A, IR10, WD repeat-containing protein 2, CORO2A, IR10, WDR2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
Background References:
  • Jin, Y., et al. Nat. Genet. 42(7):576-578(2010)
  • Marshall, T.W., et al. J. Cell. Sci. 122 (PT 17), 3061-3069 (2009) :
  • Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
  • Yoon, H.G., et al. Mol. Cell 12(3):723-734(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CORO2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the Central region of human CORO2A.
NCBI Gene ID #:
7464
NCBI Official Name:
Coronin-2A
NCBI Official Symbol:
CORO2A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
Q92828
Protein GI Number:
28381354
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q92828
User NOte:
Optimal dilutions for each application to be determined by the researcher.