ProSci

LMTK2 Antibody

Product Code:
 
PSI-62-682
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of LMTK2 using rabbit polyclonal LMTK2 Antibody.293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LMTK2 gene (Lane 2).
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Western blot analysis of LMTK2 using rabbit polyclonal LMTK2 Antibody.293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LMTK2 gene (Lane 2).

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PSI-62-682-400ul400ul£626.00
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Further Information

Additional Names:
Serine/threonine-protein kinase LMTK2, Apoptosis-associated tyrosine kinase 2, Brain-enriched kinase, hBREK, CDK5/p35-regulated kinase, CPRK, Kinase/phosphatase/inhibitor 2, Lemur tyrosine kinase 2, Serine/threonine-protein kinase KPI-2, LMTK2, AATYK2, BREK, KIAA1079, KPI2, LMR2
Application Note:
For WB starting dilution is: 1:1000
Background:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families.
Background References:
  • Kawa, S., et al., Genes Cells 9(3):219-232 (2004).
  • Hillier, L.W., et al., Nature 424(6945):157-164 (2003).
  • Scherer, S.W., et al., Science 300(5620):767-772 (2003).
  • Kesavapany, S., et al., J. Neurosci. 23(12):4975-4983 (2003).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LMTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-697 amino acids from the Central region of human LMTK2.
NCBI Gene ID #:
22853
NCBI Official Name:
Serine/threonine-protein kinase LMTK2
NCBI Official Symbol:
LMTK2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
165 kDa
Protein Accession #:
Q8IWU2
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q8IWU2
User NOte:
Optimal dilutions for each application to be determined by the researcher.