ProSci

CASQ2 Antibody

Product Code:
 
PSI-60-785
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

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PSI-60-785-400ul400ul£626.00
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Further Information

Additional Names:
Calsequestrin-2, Calsequestrin, cardiac muscle isoform, CASQ2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq].
Background References:
  • Kirchhefer, U., et al. J. Mol. Cell. Cardiol. 49(1):95-105(2010)
  • Wong, C.H., et al. Forensic Sci. Int. 192 (1-3), 53-55 (2009) :
  • Liu, J., et al. Am. J. Physiol., Cell Physiol. 297 (1), C152-C159 (2009) :
  • Hayashi, M., et al. Circulation 119(18):2426-2434(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rb
Immunogen:
This CASQ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the Central region of human CASQ2.
NCBI Gene ID #:
845
NCBI Official Name:
Calsequestrin-2
NCBI Official Symbol:
CASQ2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
O14958
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O14958
User NOte:
Optimal dilutions for each application to be determined by the researcher.