Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Peroxisomal biogenesis factor 19, 33 kDa housekeeping protein, Peroxin-19, Peroxisomal farnesylated protein, PEX19, HK33, PXF
For WB starting dilution is: 1:1000
This gene is necessary for early peroxisomal biogenesis.
It acts both as a cytosolic chaperone and as an import receptor for
peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins
that are essential for the assembly of functional peroxisomes. The
peroxisome biogenesis disorders (PBDs) are a group of genetically
heterogeneous autosomal recessive, lethal diseases characterized by
multiple defects in peroxisome function. These disorders have at
least 14 complementation groups, with more than one phenotype being
observed for some complementation groups. Although the clinical
features of PBD patients vary, cells from all PBD patients exhibit
a defect in the import of one or more classes of peroxisomal matrix
proteins into the organelle. Defects in this gene are a cause of
Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder
complementation group 14 (PBD-CG14), which is also known as
PBD-CGJ. Alternative splicing results in multiple transcript
variants.
- Mohamed, S., et al. Am. J. Med. Genet.152A (9), 2318-2321 (2010) :
- Schmidt, F., et al. J. Biol. Chem. 285(33):25410-25417(2010)
- Schueller, N., et al. EMBO J. 29(15):2491-2500(2010)
- Liu, Y., et al.Psychiatr Res (2010) In press :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Rat
This PEX19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human PEX19.
5824
Peroxisomal biogenesis factor 19
PEX19
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
P40855
729723
This antibody is purified through a protein A column, followed by peptide affinity purification.
Signal Transduction
P40855
Optimal dilutions for each application to be determined by the researcher.