ProSci

CLK1 Antibody

Product Code:
 
PSI-62-968
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of anti-hCLK1-C84 Pab in Y79 cell line lysate.
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Western blot analysis of anti-hCLK1-C84 Pab in Y79 cell line lysate.

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PSI-62-968-400ul400ul£626.00
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Further Information

Additional Names:
Dual specificity protein kinase CLK1, CDC-like kinase 1, CLK1, CLK
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection.
Background References:
  • Prasad, J., et al., Mol. Cell. Biol. 23(12):4139-4149 (2003). Talmadge, C.B., et al., Hum. Genet. 103(4):523-524 (1998). Hanes, J., et al., J. Mol. Biol. 244(5):665-672 (1994). Johnson, K.W., et al., J. Biol. Chem. 266(6):3402-3407 (1991). Ben-David, Y., et al., EMBO J. 10(2):317-325 (1991).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CLK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the N-terminal region of human CLK1.
NCBI Gene ID #:
1195
NCBI Official Name:
Dual specificity protein kinase CLK1
NCBI Official Symbol:
CLK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
P49759
Protein GI Number:
206729857
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
P49759
User NOte:
Optimal dilutions for each application to be determined by the researcher.