ProSci

RGS11 Antibody

Product Code:
 
PSI-58-884
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in HL-60 cell line lysates (35ug/lane).
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Western blot analysis in HL-60 cell line lysates (35ug/lane).

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PSI-58-884-400ul400ul£626.00
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Further Information

Additional Names:
Regulator of G-protein signaling 11, RGS11, RGS11
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Background References:
  • Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)
  • Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
  • Saleem, Y., et al. Biochem. Biophys. Res. Commun. 386(1):65-70(2009)
  • Martin, J., et al. Nature 432(7020):988-994(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RGS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human RGS11.
NCBI Gene ID #:
8786
NCBI Official Name:
Regulator of G-protein signaling 11
NCBI Official Symbol:
RGS11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
O94810
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O94810
User NOte:
Optimal dilutions for each application to be determined by the researcher.