ProSci

TSPAN7 Antibody

Product Code:
 
PSI-61-693
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of TSPAN7 Antibody in CEM cell line lysates (35ug/lane)
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Flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Western blot analysis of TSPAN7 Antibody in CEM cell line lysates (35ug/lane)
Flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

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PSI-61-693-400ul400ul£626.00
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Further Information

Additional Names:
Tetraspanin-7, Tspan-7, Cell surface glycoprotein A15, Membrane component chromosome X surface marker 1, T-cell acute lymphoblastic leukemia-associated antigen 1, TALLA-1, Transmembrane 4 superfamily member 2, CD231, TSPAN7, A15, DXS1692E, MXS1, TM4SF2
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
TSPAN7 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.
Background References:
  • Radhakrishnan, Y., et al. Biol. Reprod. 81(4):647-656(2009)
  • Guilmatre, A., et al. Arch. Gen. Psychiatry 66(9):947-956(2009)
  • Noor, A., et al. Psychiatr. Genet. 19(3):154-155(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This TSPAN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-124 amino acids from the Central region of human TSPAN7.
NCBI Gene ID #:
7102
NCBI Official Name:
Tetraspanin-7
NCBI Official Symbol:
TSPAN7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
P41732
Protein GI Number:
17380550
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P41732
User NOte:
Optimal dilutions for each application to be determined by the researcher.