ProSci

KRT6C Antibody

Product Code:
 
PSI-57-552
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in A549 cell line lysates (35ug/lane).
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KRT6C Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human esophagus carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in A549 cell line lysates (35ug/lane).
KRT6C Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human esophagus carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.

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PSI-57-552-400ul400ul£626.00
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Further Information

Additional Names:
Keratin, type II cytoskeletal 6C, Cytokeratin-6C, CK-6C, Cytokeratin-6E, CK-6E, Keratin K6h, Keratin-6C, K6C, Type-II keratin Kb12, KRT6C, KRT6E
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq].
Background References:
  • Bowden, P.E. J. Invest. Dermatol. 130(2):336-338(2010)
  • Wilson, N.J., et al. J. Invest. Dermatol. 130(2):425-429(2010)
  • Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
  • Scherer, S.E., et al. Nature 440(7082):346-351(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KRT6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the N-terminal region of human KRT6C.
NCBI Gene ID #:
286887
NCBI Official Name:
Keratin, type II cytoskeletal 6C
NCBI Official Symbol:
KRT6C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
P48668
Protein GI Number:
59803089
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P48668
User NOte:
Optimal dilutions for each application to be determined by the researcher.