ProSci

JIK Antibody

Product Code:
 
PSI-62-589
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western blot analysis of TAOK3 using rabbit polyclonal TAOK3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TAOK3 gene (Lane 2).
2 / 2
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with TAOK3 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of TAOK3 using rabbit polyclonal TAOK3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TAOK3 gene (Lane 2).
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with TAOK3 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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PSI-62-589-400ul400ul£626.00
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Further Information

Additional Names:
Serine/threonine-protein kinase TAO3, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated antigen HD-CL-09, Dendritic cell-derived protein kinase, JNK/SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, hKFC-A, Thousand and one amino acid protein 3, TAOK3, DPK, JIK, KDS, MAP3K18
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
TAOK3 is negatively regulated by epidermal growth factor (EGF) and Inhibits the basal activity of Jun kinase. When TAOK3 is overexpressed, it may activate ERK1/ERK2 and JNK/SAPK.
Background References:
  • Hartmann,T.B.,Br. J. Dermatol. 150 (2), 252-258 (2004)
  • Yustein,J.T.,Oncogene 22 (40), 6129-6141 (2003)
  • Yoneda,T.,J. Biol. Chem. 276 (17), 13935-13940 (2001)
  • Zhang,W.,Biochem. Biophys. Res. Commun. 274 (3), 872-879 (2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat, Xenopus
Immunogen:
This JIK (TAOK3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-700 amino acids from the C-terminal region of human JIK (TAOK3).
NCBI Gene ID #:
51347
NCBI Official Name:
Serine/threonine-protein kinase TAO3
NCBI Official Symbol:
TAOK3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
105 kDa
Protein Accession #:
Q9H2K8
Protein GI Number:
78099183
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q9H2K8
User NOte:
Optimal dilutions for each application to be determined by the researcher.