Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Integrin-linked protein kinase, 59 kDa serine/threonine-protein kinase, ILK-1, ILK-2, p59ILK, ILK, ILK1, ILK2
For IHC-P starting dilution is: 1:50~100
For WB starting dilution is: 1:1000
Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
- Li, Y., et al., J. Clin. Invest. 112(4):503-516 (2003).
- Troussard, A.A., et al., J. Biol. Chem. 278(25):22374-22378 (2003).
- Marotta, A., et al., Br. J. Cancer 88(11):1755-1762 (2003).
- Cordes, N., et al., Br. J. Cancer 88(9):1470-1479 (2003).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
This ILK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from human ILK.
3611
Integrin-linked protein kinase
ILK
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Q13418
9973397
This antibody is purified through a protein A column, followed by peptide affinity purification.
Signal Transduction
Q13418
Optimal dilutions for each application to be determined by the researcher.