Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
Receptor-type tyrosine-protein phosphatase epsilon, Protein-tyrosine phosphatase epsilon, R-PTP-epsilon, PTPRE
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
The protein encoded by this gene is a member of the
protein tyrosine phosphatase (PTP) family. PTPs are known to be
signaling molecules that regulate a variety of cellular processes
including cell growth, differentiation, mitotic cycle, and
oncogenic transformation. Two alternatively spliced transcript
variants of this gene have been reported, one of which encodes a
receptor-type PTP that possesses a short extracellular domain, a
single transmembrane region, and two tandem intracytoplasmic
catalytic domains; Another one encodes a PTP that contains a
distinct hydrophilic N-terminus, and thus represents a
nonreceptor-type isoform of this PTP. Studies of the similar gene
in mice suggested the regulatory roles of this PTP in RAS related
signal transduction pathways, cytokines induced SATA signaling, as
well as the activation of voltage-gated K+ channels. [provided by
RefSeq].
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
- Barr, A.J., et al. Cell 136(2):352-363(2009)
- Kraut-Cohen, J., et al. J. Biol. Chem. 283(8):4612-4621(2008)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat
This PTPRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PTPRE.
5791
Receptor-type tyrosine-protein phosphatase epsilon
PTPRE
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
81 kDa
P23469
126471
This antibody is purified through a protein A column, followed by peptide affinity purification.
Signal Transduction
P23469
Optimal dilutions for each application to be determined by the researcher.