Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
ARF GTPase-activating protein GIT1, ARF GAP GIT1, Cool-associated and tyrosine-phosphorylated protein 1, CAT-1, CAT1, G protein-coupled receptor kinase-interactor 1, GRK-interacting protein 1, GIT1
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
- Sato,H., Biochem. Biophys. Res. Commun. 368 (1), 157-161 (2008)
- Jones,N.P., Mol. Cell. Biol. 27 (16), 5790-5805 (2007)
- Schmalzigaug,R., Cell. Signal. 19 (8), 1733-1744 (2007)
- Stockton,R., Mol. Biol. Cell 18 (6), 2346-2355 (2007)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat
This GIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-517 amino acids from human GIT1.
28964
ARF GTPase-activating protein GIT1
GIT1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Q9Y2X7
45645212
This antibody is purified through a protein A column, followed by peptide affinity purification.
Signal Transduction
Q9Y2X7
Optimal dilutions for each application to be determined by the researcher.