ProSci

CDH7 Antibody

Product Code:
 
PSI-57-937
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 3
Western blot analysis of anti-CDH7 Pab in K562 cell line lysates (35ug/lane)
2 / 3
Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with CDH7 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
3 / 3
❮❯

Western blot analysis of anti-CDH7 Pab in K562 cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with CDH7 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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PSI-57-937-400ul400ul£626.00
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Further Information

Additional Names:
Cadherin-7, CDH7, CDH7L1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50
Background:
CDH7 is a type II classical cadherin from the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures.
Background References:
  • Moore,R., Oncogene 23 (40), 6726-6735 (2004)
  • Kools,P., Genomics 68 (3), 283-295 (2000)
  • Shimoyama,Y., Biochem. J. 349 (PT 1), 159-167 (2000)
  • Kremmidiotis,G., Genomics 49 (3), 467-471 (1998)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Immunogen:
This CDH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from the N-terminal region of human CDH7.
NCBI Gene ID #:
1005
NCBI Official Name:
Cadherin-7
NCBI Official Symbol:
CDH7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
87 kDa
Protein Accession #:
Q9ULB5
Protein GI Number:
296434420
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9ULB5
User NOte:
Optimal dilutions for each application to be determined by the researcher.