ProSci

HIST2H2AA4 Antibody

Product Code:
 
PSI-57-382
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in K562 cell line lysates (35ug/lane).
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Western blot analysis in K562 cell line lysates (35ug/lane).

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PSI-57-382-400ul400ul£626.00
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Further Information

Additional Names:
Histone H2A type 2-A, Histone H2A2, Histone H2A/o, HIST2H2AA3, H2AFO, HIST2H2AA
Application Note:
For WB starting dilution is: 1:1000
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.
Background References:
  • Braastad, C.D., et al. Gene 342(1):35-40(2004)
  • Marzluff, W.F., et al. Genomics 80(5):487-498(2002)
  • Mannironi, C., et al. DNA Cell Biol. 13(2):161-170(1994)
  • Allen, B.S., et al. Genomics 10(2):486-488(1991)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat, Bovine, Mouse
Immunogen:
This HIST2H2AA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the C-terminal region of human HIST2H2AA4.
NCBI Gene ID #:
723790, 8337
NCBI Official Name:
Histone H2A type 2-A
NCBI Official Symbol:
HIST2H2AA3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
14 kDa
Protein Accession #:
Q6FI13
Protein GI Number:
74757558
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q6FI13
User NOte:
Optimal dilutions for each application to be determined by the researcher.