ProSci

BRMS1 Antibody

Product Code:
 
PSI-60-513
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Hela cell line lysates (35ug/lane).
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Western blot analysis in Hela cell line lysates (35ug/lane).

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PSI-60-513-400ul400ul£626.00
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Further Information

Additional Names:
Breast cancer metastasis-suppressor 1, BRMS1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
Background References:
  • Wu, Y., et al. Cancer Lett. 293(1):82-91(2010)
  • Vaidya, K.S., et al. Cancer Lett. 281(1):100-107(2009)
  • Frolova, N., et al. Tumour Biol. 30(3):148-159(2009)
  • Martins-de-Souza, D., et al. BMC Psychiatry 9, 17 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This BRMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human BRMS1.
NCBI Gene ID #:
25855
NCBI Official Name:
Breast cancer metastasis-suppressor 1
NCBI Official Symbol:
BRMS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
Q9HCU9
Protein GI Number:
18202959
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9HCU9
User NOte:
Optimal dilutions for each application to be determined by the researcher.