Further Information
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, Beta-1,2-N-acetylglucosaminyltransferase II, GlcNAc-T II, GNT-II, Mannoside acetylglucosaminyltransferase 2, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II, MGAT2
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
MGAT2 (UDP-N-acetylglucosamine:alpha-6-D-mannoside-beta-1, 2-N-acetylglucosaminyltransferase II) is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in MGAT2 may lead to carbohydrate-deficient glycoprotein syndrome, type II.
- Yen, C.L., et al., J. Biol. Chem. 278(20):18532-18537 (2003). Chen, S.H., et al., Glycoconj. J. 15(3):301-308 (1998). Tan, J., et al., Am. J. Hum. Genet. 59(4):810-817 (1996). Tan, J., et al., Eur. J. Biochem. 231(2):317-328 (1995). D'Agostaro, G.A., et al., J. Biol. Chem. 270(25):15211-15221 (1995).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat
This MGAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human MGAT2.
4247
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
MGAT2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Q10469
1708004
This antibody is purified through a protein A column, followed by peptide affinity purification.
Q10469
Optimal dilutions for each application to be determined by the researcher.