ProSci

GABPA Antibody

Product Code:
 
PSI-57-435
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in CEM cell line lysates (35ug/lane).
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Western blot analysis in CEM cell line lysates (35ug/lane).

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PSI-57-435-400ul400ul£626.00
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Further Information

Additional Names:
GA-binding protein alpha chain, GABP subunit alpha, Nuclear respiratory factor 2 subunit alpha, Transcription factor E4TF1-60, GABPA, E4TF1A
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.
Background References:
  • Henderson, A.J., et al. Thorax 65(10):897-902(2010)
  • Eynon, N., et al. Physiol. Genomics 41(1):78-81(2010)
  • Levy, S., et al. IUBMB Life 62(3):237-246(2010)
  • Kim, Y.R., et al. J. Pathol. 220(4):446-451(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GABPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the Central region of human GABPA.
NCBI Gene ID #:
2551
NCBI Official Name:
GA-binding protein alpha chain
NCBI Official Symbol:
GABPA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
Q06546
Protein GI Number:
729553
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q06546
User NOte:
Optimal dilutions for each application to be determined by the researcher.