ProSci

BACH1 Antibody

Product Code:
 
PSI-57-890
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

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PSI-57-890-400ul400ul£626.00
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Further Information

Additional Names:
Transcription regulator protein BACH1, BTB and CNC homolog 1, HA2303, BACH1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.
Background References:
  • Miyazaki, T., et al. Cancer Sci. 101(6):1409-1416(2010)
  • Hou, W., et al. Hepatology 51(5):1494-1504(2010)
  • Gong, Z., et al. Mol. Cell 37(3):438-446(2010)
  • Zhong, J.L., et al. Free Radic. Biol. Med. 48(2):196-206(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This BACH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 670-698 amino acids from the C-terminal region of human BACH1.
NCBI Gene ID #:
571
NCBI Official Name:
Transcription regulator protein BACH1
NCBI Official Symbol:
BACH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
82 kDa
Protein Accession #:
O14867
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O14867
User NOte:
Optimal dilutions for each application to be determined by the researcher.