ProSci

IRF1 Antibody

Product Code:
 
PSI-56-084
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

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PSI-56-084-400ul400ul£626.00
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Further Information

Additional Names:
Interferon regulatory factor 1, IRF-1, IRF1
Application Note:
For WB starting dilution is: 1:1000
Background:
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
Background References:
  • Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
  • Matsuzaki, S., et al. J. Immunol. 185(8):4863-4872(2010)
  • Antonios, D., et al. J. Immunol. 185(1):89-98(2010)
  • Lou, Y.J., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(3):255-258(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Immunogen:
This IRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the Central region of human IRF1.
NCBI Gene ID #:
3659
NCBI Official Name:
Interferon regulatory factor 1
NCBI Official Symbol:
IRF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
P10914
Protein GI Number:
20178295
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P10914
User NOte:
Optimal dilutions for each application to be determined by the researcher.