ProSci

RBAK Antibody

Product Code:
 
PSI-58-617
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in 293 cell line lysates (35ug/lane).
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Western blot analysis in 293 cell line lysates (35ug/lane).

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PSI-58-617-400ul400ul£626.00
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Further Information

Additional Names:
RB-associated KRAB zinc finger protein, RB-associated KRAB repressor, hRBaK, Zinc finger protein 769, RBAK, ZNF769
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif.
Background References:
  • Trynka, G., et al. Gut 58(8):1078-1083(2009)
  • Ma, Y., et al. BMC Genomics 10, 109 (2009) :
  • Jeske, Y.W., et al. Clin. Exp. Pharmacol. Physiol. 35(4):380-385(2008)
  • So, A., et al. Clin. Endocrinol. (Oxf) 65(6):829-831(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RBAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the N-terminal region of human RBAK.
NCBI Gene ID #:
100533952, 57786
NCBI Official Name:
RB-associated KRAB zinc finger protein
NCBI Official Symbol:
RBAK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
83 kDa
Protein Accession #:
Q9NYW8
Protein GI Number:
74761820
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NYW8
User NOte:
Optimal dilutions for each application to be determined by the researcher.