ProSci

SP3 Antibody

Product Code:
 
PSI-57-717
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 1
Western blot analysis in HepG2 cell line lysates (35ug/lane).
❮❯

Western blot analysis in HepG2 cell line lysates (35ug/lane).

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-57-717-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
Transcription factor Sp3, SPR-2, SP3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.
Background References:
  • Yamaguchi, K., et al. Biochem. J. 430(1):107-117(2010)
  • Jutooru, I., et al. J. Biol. Chem. 285(33):25332-25344(2010)
  • Markovics, J.A., et al. J. Biol. Chem. 285(32):24695-24706(2010)
  • Eckerstorfer, P., et al. Mol. Immunol. 47 (11-12), 2094-2102 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the Central region of human SP3.
NCBI Gene ID #:
6670
NCBI Official Name:
Transcription factor Sp3
NCBI Official Symbol:
SP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
82 kDa
Protein Accession #:
Q02447
Protein GI Number:
30923147
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q02447
User NOte:
Optimal dilutions for each application to be determined by the researcher.