ProSci

RAD23A Antibody

Product Code:
 
PSI-57-814
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Hela cell line lysates (35ug/lane).
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Western blot analysis in Hela cell line lysates (35ug/lane).

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PSI-57-814-400ul400ul£626.00
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Further Information

Additional Names:
UV excision repair protein RAD23 homolog A, HR23A, hHR23A, RAD23A
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. [provided by RefSeq].
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
  • Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
  • Li, G., et al. PLoS ONE(6), E11371 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This RAD23A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human RAD23A.
NCBI Gene ID #:
5886
NCBI Official Name:
UV excision repair protein RAD23 homolog A
NCBI Official Symbol:
RAD23A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
P54725
Protein GI Number:
1709983
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P54725
User NOte:
Optimal dilutions for each application to be determined by the researcher.