ProSci

TMED6 Antibody

Product Code:
 
PSI-58-608
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in HL-60 cell line lysates (35ug/lane).
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Western blot analysis in HL-60 cell line lysates (35ug/lane).

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PSI-58-608-400ul400ul£626.00
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Further Information

Additional Names:
Transmembrane emp24 domain-containing protein 6, p24 family protein gamma-5, p24gamma5, TMED6
Application Note:
For WB starting dilution is: 1:1000
Background:
TMED6 (transmembrane emp24 domain-containing protein 6) is a 240 amino acid single-pass type I membrane protein that belongs to the EMP24/GP25L family and contains one GOLD domain. The gene that encodes TMED6 contains around 8,564 bases and maps to human chromosome 16q22.1. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3% of the human genome and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, when mutated, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. Alterations in the CREB gene and NOD2 gene, both of which are located on chromosome 16, result in Rubinstein-Taybi syndrome and Crohn's disease, respectively. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
Background References:
  • Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TMED6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-153 amino acids from the Central region of human TMED6.
NCBI Gene ID #:
146456
NCBI Official Name:
Transmembrane emp24 domain-containing protein 6
NCBI Official Symbol:
TMED6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
Q8WW62
Protein GI Number:
166897636
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8WW62
User NOte:
Optimal dilutions for each application to be determined by the researcher.