ProSci

DGCR14 Antibody

Product Code:
 
PSI-57-364
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in K562 cell line lysates (35ug/lane).
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Western blot analysis in K562 cell line lysates (35ug/lane).

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PSI-57-364-400ul400ul£626.00
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Further Information

Additional Names:
Protein DGCR14, DiGeorge syndrome critical region 13, DiGeorge syndrome critical region 14, DiGeorge syndrome protein H, DGS-H, Protein ES2, DGCR14, DGCR13, DGSH, DGSI, ES2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus.
Background References:
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
  • Wang, H., et al.Neural Transm 113(10):1551-1561(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DGCR14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the Central region of human DGCR14.
NCBI Gene ID #:
8220
NCBI Official Name:
Protein DGCR14
NCBI Official Symbol:
DGCR14
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
Q96DF8
Protein GI Number:
27805463
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q96DF8
User NOte:
Optimal dilutions for each application to be determined by the researcher.