ProSci

PAIP1 Antibody

Product Code:
 
PSI-60-273
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

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PSI-60-273-400ul400ul£626.00
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Further Information

Additional Names:
Polyadenylate-binding protein-interacting protein 1, PABP-interacting protein 1, PAIP-1, Poly(A)-binding protein-interacting protein 1, PAIP1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
Background References:
  • Kanaan, A.S., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 65 (PT 10), 1060-1064 (2009) :
  • Martineau, Y., et al. Mol. Cell. Biol. 28(21):6658-6667(2008)
  • Fortna, A., et al. PLoS Biol.(7), E207 (2004) :
  • Roy, G., et al. Mol. Cell. Biol. 22(11):3769-3782(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PAIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-49 amino acids from the N-terminal region of human PAIP1.
NCBI Gene ID #:
10605
NCBI Official Name:
Polyadenylate-binding protein-interacting protein 1
NCBI Official Symbol:
PAIP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
Q9H074
Protein GI Number:
46397025
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9H074
User NOte:
Optimal dilutions for each application to be determined by the researcher.