ProSci

ZMYND10 Antibody

Product Code:
 
PSI-56-227
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 3
Western blot analysis in CEM cell line lysates (35ug/lane).
2 / 3
ZMYND10 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
3 / 3
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Western blot analysis in CEM cell line lysates (35ug/lane).
ZMYND10 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

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PSI-56-227-400ul400ul£626.00
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Further Information

Additional Names:
Zinc finger MYND domain-containing protein 10, Protein BLu, ZMYND10, BLU
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
BLU is a candidate tumor suppressor gene, that spans 4.5 kb on 3p21.3. It encodes a 50 kd protein, which is commonly found in transcription repressors. It is suspected that BLU has a function in cell cycle progression. BLU is a stress-responsive gene regulated by E2F.12 It is commonly found to be downregulated in non-small cell lung cancer, esophagus squamous cell carcinoma and nasopharyngeal carcinoma (NPC).
Background References:
  • Shao, Y., et al. Cancer Invest. 28(6):642-648(2010)
  • Lorente, A., et al. Brain Pathol. 19(2):279-292(2009)
  • Muzny, D.M., et al. Nature 440(7088):1194-1198(2006)
  • Marsit, C.J., et al. Int. J. Cancer 114(2):219-223(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ZMYND10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-348 amino acids from the Central region of human ZMYND10.
NCBI Gene ID #:
51364
NCBI Official Name:
Zinc finger MYND domain-containing protein 10
NCBI Official Symbol:
ZMYND10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
O75800
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O75800
User NOte:
Optimal dilutions for each application to be determined by the researcher.