ProSci

CTBP1 Antibody

Product Code:
 
PSI-55-512
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:2000 dilution Lane 1: HepG2 whole cell lysates Lane 2: SH-SY5Y whole cell lysates Lane 3: mouse brain lysates Lane 4: Raji whole cell lysates Lysates/proteins at 20 ug per lane.
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Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).
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Western Blot at 1:2000 dilution Lane 1: HepG2 whole cell lysates Lane 2: SH-SY5Y whole cell lysates Lane 3: mouse brain lysates Lane 4: Raji whole cell lysates Lysates/proteins at 20 ug per lane.
Western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).

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PSI-55-512-400ul400ul£626.00
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Further Information

Additional Names:
C-terminal-binding protein 1, CtBP1, 111-, CTBP1, CTBP
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
Background References:
  • Roukens, M.G., et al. Nat. Cell Biol. 12(10):933-942(2010)
  • Choi, H.J., et al. Biochem. Biophys. Res. Commun. 400(3):396-402(2010)
  • Merrill, J.C., et al. J. Mol. Biol. 398(5):657-671(2010)
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CTBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-438 amino acids from the C-terminal region of human CTBP1.
NCBI Gene ID #:
1487
NCBI Official Name:
C-terminal-binding protein 1
NCBI Official Symbol:
CTBP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
Q13363
Protein GI Number:
6014741
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,
Swissprot #:
Q13363
User NOte:
Optimal dilutions for each application to be determined by the researcher.