ProSci

TNFRSF8-Y479 Antibody

Product Code:
 
PSI-61-707
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of TNFRSF8-Y479 in mouse liver tissue lysates (35ug/lane)
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TNFRSF8-Y479 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNFRSF8-Y479 Antibody for immunohistochemistry.
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Western blot analysis of TNFRSF8-Y479 in mouse liver tissue lysates (35ug/lane)
TNFRSF8-Y479 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNFRSF8-Y479 Antibody for immunohistochemistry.

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PSI-61-707-400ul400ul£626.00
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Further Information

Additional Names:
Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
TNFRSF8 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
Background References:
  • Braun, F.K., et al. J. Invest. Dermatol. 130(3):826-840(2010)
  • Azarpira, N., et al. SaudiKidney Dis Transpl 21(1):31-36(2010)
  • Edinger, J.T., et al. Am. J. Surg. Pathol. 33(12):1860-1868(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TNFRSF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-487 amino acids from human TNFRSF8.
NCBI Gene ID #:
943
NCBI Official Name:
Tumor necrosis factor receptor superfamily member 8
NCBI Official Symbol:
TNFRSF8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
64 kDa
Protein Accession #:
P28908
Protein GI Number:
115978
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Immunology,Signal Transduction
Swissprot #:
P28908
User NOte:
Optimal dilutions for each application to be determined by the researcher.