Further Information
ATP-binding cassette sub-family D member 2, Adrenoleukodystrophy-like 1, Adrenoleukodystrophy-related protein, hALDR, ABCD2, ALD1, ALDL1, ALDR, ALDRP
For WB starting dilution is: 1:1000
ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.
- Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
- Maier, E.M., et al. Biochem. Biophys. Res. Commun. 377(1):176-180(2008)
- Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Rat
This ABCD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-298 amino acids from the Central region of human ABCD2.
225
ATP-binding cassette sub-family D member 2
ABCD2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
83 kDa
Q9UBJ2
12643305
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Obesity,Signal Transduction
Q9UBJ2
Optimal dilutions for each application to be determined by the researcher.