Further Information
DnaJ homolog subfamily C member 2, M-phase phosphoprotein 11, Zuotin-related factor 1, DnaJ homolog subfamily C member 2, N-terminally processed, DNAJC2, MPHOSPH11, MPP11, ZRF1
For WB starting dilution is: 1:1000
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6.
- Hatzold, J., et al. PLoS Biol.(4), E84 (2008) :
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Otto, H., et al. Proc. Natl. Acad. Sci. U.S.A. 102(29):10064-10069(2005)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
This DNAJC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-255 amino acids from the Central region of human DNAJC2.
27000
DnaJ homolog subfamily C member 2
DNAJC2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Q99543
296439472
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Signal Transduction
Q99543
Optimal dilutions for each application to be determined by the researcher.