ProSci

EXTL2 Antibody

Product Code:
 
PSI-63-849
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of EXTL2 Antibody in MDA-MB231 cell line lysates (35ug/lane).
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Western blot analysis of EXTL2 Antibody in mouse cerebellum tissue lysates (35ug/lane)
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Western blot analysis of EXTL2 Antibody in MDA-MB231 cell line lysates (35ug/lane).
Western blot analysis of EXTL2 Antibody in mouse cerebellum tissue lysates (35ug/lane)

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PSI-63-849-400ul400ul£626.00
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Further Information

Additional Names:
Exostosin-like 2, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, Alpha-GalNAcT EXTL2, EXT-related protein 2, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Processed exostosin-like 2, EXTL2, EXTR2
Application Note:
For WB starting dilution is: 1:1000
Background:
EXTL2 is a glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.
Background References:
  • Kaidonis,X., et.al, Eur. J. Hum. Genet. 18 (2), 194-199 (2010)
  • Sobhany,M., et.al, J. Biol. Chem. 280 (25), 23441-23445 (2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EXTL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-295 amino acids from the C-terminal region of human EXTL2.
NCBI Gene ID #:
2135
NCBI Official Name:
Exostosin-like 2
NCBI Official Symbol:
EXTL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
Q9UBQ6
Protein GI Number:
9296986
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q9UBQ6
User NOte:
Optimal dilutions for each application to be determined by the researcher.