ProSci

FKBP1B Antibody

Product Code:
 
PSI-63-255
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of FKBP1B antibody in 293 cell line lysates (35ug/lane)
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Western blot analysis of FKBP1B antibody in mouse cerebellum tissue lysates (35ug/lane)
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Confocal immunofluorescent analysis of FKBP1B Antibody with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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Western blot analysis of FKBP1B antibody in 293 cell line lysates (35ug/lane)
Western blot analysis of FKBP1B antibody in mouse cerebellum tissue lysates (35ug/lane)
Confocal immunofluorescent analysis of FKBP1B Antibody with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

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PSI-63-255-400ul400ul£626.00
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Further Information

Additional Names:
Peptidyl-prolyl cis-trans isomerase FKBP1B, PPIase FKBP1B, 126 kDa FK506-binding protein, 126 kDa FKBP, FKBP-126, FK506-binding protein 1B, FKBP-1B, Immunophilin FKBP126, Rotamase, h-FKBP-12, FKBP1B, FKBP126, FKBP1L, FKBP9, OTK4
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50
Background:
FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. The protein is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.
Background References:
  • Arakawa H., Nagase H.Biochem. Biophys. Res. Commun. 200:836-843(1994)
  • Lam E., Martin M.M., Timerman A.P.Biol. Chem. 270:26511-26522(1995)
  • Deivanayagam C.C., Carson M.Acta Crystallogr.56:266-271(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Rabbit, Rat
Immunogen:
This FKBP1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human FKBP1B.
NCBI Gene ID #:
2281
NCBI Official Name:
Peptidyl-prolyl cis-trans isomerase FKBP1B
NCBI Official Symbol:
FKBP1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
12 kDa
Protein Accession #:
P68106
Protein GI Number:
61224185
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Immunology,Neuroscience
Swissprot #:
P68106
User NOte:
Optimal dilutions for each application to be determined by the researcher.