ProSci

SYK Antibody

Product Code:
 
PSI-56-631
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:2000 dilution Lane 1: THP-1 whole cell lysates Lane 2: Ramos whole cell lysates Lane 3: mouse spleen lysates Lysates/proteins at 20 ug per lane.
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Western blot analysis in 293 cell line lysates (35ug/lane).
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Western Blot at 1:2000 dilution Lane 1: THP-1 whole cell lysates Lane 2: Ramos whole cell lysates Lane 3: mouse spleen lysates Lysates/proteins at 20 ug per lane.
Western blot analysis in 293 cell line lysates (35ug/lane).

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PSI-56-631-400ul400ul£626.00
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Further Information

Additional Names:
Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk, SYK
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Background References:
  • Thomas, D.H., et al. Blood 116(14):2570-2578(2010)
  • Poeck, H., et al. J. Mol. Med. 88(8):745-752(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Pechloff, K., et al. J. Exp. Med. 207(5):1031-1044(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Pig
Immunogen:
This SYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-305 amino acids from human SYK.
NCBI Gene ID #:
6850
NCBI Official Name:
Tyrosine-protein kinase SYK
NCBI Official Symbol:
SYK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
P43405
Protein GI Number:
1174527
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P43405
User NOte:
Optimal dilutions for each application to be determined by the researcher.