ProSci

BRDG 1 Antibody

Product Code:
 
PSI-57-968
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of anti-STAP1 Antibody (F56) in mouse kidney tissue lysates (35ug/lane)
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Western blot analysis of STAP1 using rabbit polyclonal STAP1 Antibody (F56) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the STAP1 gene.
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Western blot analysis of anti-STAP1 Antibody (F56) in mouse kidney tissue lysates (35ug/lane)
Western blot analysis of STAP1 using rabbit polyclonal STAP1 Antibody (F56) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the STAP1 gene.

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PSI-57-968-400ul400ul£626.00
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Further Information

Additional Names:
Signal-transducing adaptor protein 1, STAP-1, BCR downstream-signaling protein 1, Docking protein BRDG1, Stem cell adaptor protein 1, STAP1, BRDG1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
STAP1 functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity.
Background References:
  • Ma,J., Atherosclerosis 191 (1), 63-72 (2007)
  • Beausoleil,S.A., Nat. Biotechnol. 24 (10), 1285-1292 (2006)
  • Gstaiger,M., Science 302 (5648), 1208-1212 (2003)
  • Minoguchi,M., J. Biol. Chem. 278 (13), 11182-11189 (2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This BRDG 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human BRDG 1.
NCBI Gene ID #:
26228
NCBI Official Name:
Signal-transducing adaptor protein 1
NCBI Official Symbol:
STAP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
Q9ULZ2
Protein GI Number:
62511239
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q9ULZ2
User NOte:
Optimal dilutions for each application to be determined by the researcher.