ProSci

KCNQ5 Antibody

Product Code:
 
PSI-58-714
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western Blot at 1:1000 dilution + human skeletal muscle lysate Lysates/proteins at 20 ug per lane.
2 / 2
Western blot analysis in mouse heart tissue lysates (35ug/lane).
❮❯

Western Blot at 1:1000 dilution + human skeletal muscle lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in mouse heart tissue lysates (35ug/lane).

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PSI-58-714-400ul400ul£626.00
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Further Information

Additional Names:
Potassium voltage-gated channel subfamily KQT member 5, KQT-like 5, Potassium channel subunit alpha KvLQT5, Voltage-gated potassium channel subunit Kv75, KCNQ5
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Bailey, S.D., et al. Diabetes Care (2010) In press :
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Roura-Ferrer, M., et al. Cell. Physiol. Biochem. 24 (5-6), 325-334 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KCNQ5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-809 amino acids from the C-terminal region of human KCNQ5.
NCBI Gene ID #:
56479
NCBI Official Name:
Potassium voltage-gated channel subfamily KQT member 5
NCBI Official Symbol:
KCNQ5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
102 kDa
Protein Accession #:
Q9NR82
Protein GI Number:
122065285
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9NR82
User NOte:
Optimal dilutions for each application to be determined by the researcher.