Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
Serum paraoxonase/arylesterase 2, PON 2, Aromatic esterase 2, A-esterase 2, Serum aryldialkylphosphatase 2, PON2
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IF starting dilution is: 1:10~50
PON2 is a member of the paraoxonase gene family,
which includes three known members located adjacent to each other
on the long arm of chromosome 7. The encoded protein is
ubiquitously expressed in human tissues, membrane-bound, and may
act as a cellular antioxidant, protecting cells from oxidative
stress. Hydrolytic activity against acylhomoserine lactones,
important bacterial quorum-sensing mediators, suggests the encoded
protein may also play a role in defense responses to pathogenic
bacteria. Mutations in this gene may be associated with vascular
disease and a number of quantitative phenotypes related to
diabetes.
- Sanghera, D.K., et al. Am. J. Hum. Genet. 62(1):36-44(1998)
- Hegele, R.A., et al. J. Clin. Endocrinol. Metab. 82(10):3373-3377(1997)
- Primo-Parmo, S.L., et al. Genomics 33(3):498-507(1996)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This PON2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-101 amino acids from the Central region of human PON2.
5445
Serum paraoxonase/arylesterase 2
PON2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Q15165
325511384
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Neuroscience,Signal Transduction
Q15165
Optimal dilutions for each application to be determined by the researcher.