ProSci

GPER Antibody

Product Code:
 
PSI-58-136
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse liver tissue lysates (35ug/lane).
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
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Western blot analysis in mouse liver tissue lysates (35ug/lane).
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

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PSI-58-136-400ul400ul£626.00
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Further Information

Additional Names:
G-protein coupled estrogen receptor 1, Chemoattractant receptor-like 2, Flow-induced endothelial G-protein coupled receptor 1, FEG-1, G protein-coupled estrogen receptor 1, G-protein coupled receptor 30, GPCR-Br, IL8-related receptor DRY12, Lymphocyte-derived G-protein coupled receptor, LYGPR, Membrane estrogen receptor, mER, GPER1, CEPR, CMKRL2, DRY12, GPER, GPR30
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq].
Background References:
  • Patel, V.H., et al. Int. J. Mol. Med. 26(2):193-199(2010)
  • Ignatov, A., et al. Breast Cancer Res. Treat. 123(1):87-96(2010)
  • Li, Y., et al. Mol. Endocrinol. 24(5):969-980(2010)
  • Kang, L., et al. Mol. Endocrinol. 24(4):709-721(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GPER antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the C-terminal region of human GPER.
NCBI Gene ID #:
2852
NCBI Official Name:
G-protein coupled estrogen receptor 1
NCBI Official Symbol:
GPER1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q99527
Protein GI Number:
3023539
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Neuroscience,Signal Transduction,Growth Factor
Swissprot #:
Q99527
User NOte:
Optimal dilutions for each application to be determined by the researcher.